COLOXYL with SENNA is a dual action formula providing constipation relief that starts to work within 6-12 hours. The combination of two active ingredients helps make bowel movements easier by both softening stools and stimulating the muscles in the bowel. It is available in easy to swallow tablets for overnight relief. And it is suitable for use in adults and children 12 years and over, including those who take constipation-inducing medications, such as opioids. Check with your doctor or pharmacist, if using in conjunction with opioids.